Thursday 17 July 2014

Acetylsalicylic acid tablets with glycine | ASCARDILL- (Aspirin with Glycine Tablets)- TAJ PHARMA

ASCARDILL- (Aspirin with Glycine Tablets)- TAJ PHARMA

Aspirin with Glycine Tablets



Aspirin with Glycine Tablets is used as an analgesic to rapidly relieve minor to moderate aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Glycine is an organic compound, it improves the gastric absorption of acetylsalicylic acid.

Name of Drug
Generic Aspirin with Glycine: Each uncoated tablet of Ascardill (Generic Aspirin with Glycine Tablets) contains Aspirin 75 /150 mg + Glycine 37.5 / 75 mg. 



Aspirin is used as an analgesic for rapid relief of minor to moderate aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Glycine is an organic compound, it improves the gastric absorption of acetylsalicylic acid. Aspirin is also used long-term, at low doses, to help prevent heart attacks, strokes, and blood clot formation in people at high risk for developing blood clots. It has also been established, that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack and stroke.

Aspirin is used for the treatment of inflammation, fever, and pain that results from many forms of arthritis, including rheumatoid arthritis, juvenile arthritis, systemic lupus erythematosus, ankylosing spondylitis, Reiter's syndrome, and osteoarthritis, as well as for soft tissue injuries, such as tendinitis and bursitis. Aspirin also is used for rapid relief of mild to moderate pain and fever in other inflammatory conditions.

Aspirin should be taken with food.
Usual doses for mild to moderate pain are 325 mg every 4 hours
Doses for rheumatoid arthritis include 325 mg every 4-6 hours
Heart attacks are prevented with 75, 150 or 325 mg daily. 

Aspirin is a nonsteroidal anti inflammatory drug (NSAID) effective in treating fever, pain, and inflammation in the body. It also prevents blood clots (i.e., is antithrombotic). As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including headaches, injury, menstrual cramps, arthritis, and other musculoskeletal conditions. They all work by reducing the levels of prostaglandins, chemicals that are released when there is inflammation and that cause pain and fever. NSAIDs block the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain, and fever are reduced. Inhibition of prostaglandins also reduces the function of platelets and the ability of blood to clot. Generic Aspirin inhibits the function of platelets in a manner that is different from other NSAIDs, and its antithrombotic effects last longer than other NSAIDs. Thus, Aspirin is used for preventing heart attacks and strokes.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine.

  • Indigestion (dyspepsia).
  • Nausea.
  • Stomach or intestinal discomfort.
  • Sensation of ringing, or other noise in the ears (tinnitus).
  • Worsening of asthma.
  • Increased bleeding time.
  • Ulceration or bleeding in the stomach or intestines.
  • Blood disorders.

Monday 7 July 2014

Taj Pharmaceuticals, taj pharma, taj drugs, Afrelect, Rasigiline tablets, taj drugs, monoamine oxidase inhibitors, Taj pharma brands, pharma brands.


AFRELECT (rasagiline tablets) is a medication used for treatment of many symptoms of Parkinson's disease. Because Afrelect helps prevent dopamine in your brain, it can help you move freely so everyday activites may become less difficult. Afrelect is a once-daily medication that can be taken alone in early Parkinson's disease or with other Parkinson's medications as the disease progresses.


 KEY POINTS:
  • Rasagiline, like selegiline, is an irreversible monoamine oxidase type B (MAO-B) inhibitor
    It inhibits the breakdown of dopamine in the brain and can be used as monotherapy or as an adjunct to levodopa.
  • Rasagiline (1 mg) is taken once a day
    Rasagiline can be taken at any time of day. Increasing the dose does not increase the therapeutic effect but does increase the risk of adverse events.
  • Adjunctive therapy may increase levodopa-associated adverse events such as dyskinesia
    Incidence of hallucination and hypersomnolence was similar to that for placebo or levodopa alone in trials. Impulse control disorders were not observed in trials.
  • There are no direct comparisons with dopamine agonists or selegiline; efficacy as adjunctive therapy may be similar to that of entacapone
    Indirect comparisons as adjunctive therapy suggest less efficacy than dopamine agonists.
  • There is a risk of hypertensive crisis or serotonin toxicity if rasagiline is used concomitantly with certain medications
    Use with other MAO inhibitors, dextromethorphan and certain opioid analgesics is contraindicated. Obtain specialist advice before combining with antidepressants.
  • Rasagiline is contraindicated in people with liver impairment
    Rasagiline is metabolised in the liver by the enzyme CYP1A2. Potent inhibitors of CYP1A2 (e.g. ciprofloxacin, cimetidine or fluvoxamine) are contraindicated.



 IMPORTANT SAFETY INFORMATION ABOUT AFRELECT
  • Do not take AFRELECT if you are taking meperidine as it could result in a serious reaction such as coma or death. Also, do not take AFRELECT with tramadol, methadone, propoxyphene, dextromethorphan, St. John's wort, or cyclobenzaprine.
  • You also should not take AFRELECT with other monoamine oxidase inhibitors (MAOIs).
  • Inform your physician if you are taking, or planning to take, any prescription or over-the-counter drugs, especially antidepressants and ciprofloxacin.
  • If you have moderate to severe liver disease, you should not take AFRELECT.
  • You should not exceed a dose of 1 mg per day of AFRELECT in order to prevent a possibly dangerous increase in blood pressure. All PD patients should be monitored for melanoma (skin cancer) on a regular basis.
  • Side effects seen with AFRELECT alone are flu syndrome, joint pain, depression, and indigestion.
  • Side effects seen with AFRELECT when taken with levodopa are uncontrolled movements (dyskinesia), accidental injury, weight loss, low blood pressure when standing, vomiting, anorexia, joint pain, abdominal pain, nausea, constipation, dry mouth, rash, abnormal dreams, and fall.

HOW TO USE AFRELECT (RASAGILINE TABLETS)?
Use Afrelect (rasagiline tablets) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
  • Take rasagiline by mouth with or without food.
  • Do not suddenly stop taking rasagiline without checking with your doctor. You may experience side effects such as fever or confusion.
  • If you miss a dose of rasagiline, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use rasagiline.

POSSIBLE SIDE EFFECTS OF AFRELECT (RASIGILINE TABLETS)
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation, diarrhea; drowsiness; dry mouth; flu-like symptoms; headache; joint pain; loss of appetite, mild stomach pain; stomach upset; stuffy nose; weight loss.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or bloody stools; blood in the urine; blurred vision or other vision changes; burning, numbness, or tingling; changes in sexual ability or desire; chest pain; confusion; decreased coordination; enlarged pupils; eye pain or inflammation; fainting; fast or irregular heartbeat; fever; hallucinations; inability to sit still; mental or mood changes (eg, agitation, depression, paranoia); one-sided weakness; seizures; sensitivity to light; severe or persistent headache, dizziness, or light-headedness; severe or persistent stomach pain or diarrhea; shortness of breath; skin changes; sore or stiff neck; speech problems; stiff muscles; tremor; trouble thinking or walking; unexplained nausea or vomiting; unusual sweating.

AFRELECT (RASAGILINE TABLETS) DOSAGE INFORMATION:
Usual Adult Dose for Parkinson's Disease:
Monotherapy: 1 mg orally once daily

Adjunctive therapy (in combination with levodopa): 0.5 mg orally once daily. If a sufficient clinical response is not achieved, the dose may be increased to 1 mg orally daily.

OTHER DRUGS THAT MAY AFFECT AFRELECT (RASAGILINE TABLETS):
Tell your doctor about all other medicines you have used within the past 14 days, especially:
  • Ciprofloxacin ;
  • Over-the-counter cough, cold, or allergy medicines; or
  • An antidepressant such as amitriptyline, citalopram, doxepin, desipramine, duloxetine, fluoxetine, fluvoxamine, imipramine, nortriptyline, paroxetine, sertraline, venlafaxine, and others.

Saturday 5 July 2014

Adrenilan, Taj Pharmaceuticals, Taj Pharma, Pharma India Brands, Pharma Brands, Taj Drugs, Taj brands, Vasodilator


ISOXSUPRINE (eye SOX syoo preen) is a type of vasodilator. This medicine is used to treat problems that result from poor blood circulation. It is also used to treat the symptoms of certain types of dementia. This medication is prescribed for peripheral vascular disease, relief of symptoms associated with cerebrovascular insufficiency, and premature labor.  It relaxes blood vessels, which makes them wider and allows blood to pass through them more easily.
 
When it is not to be taken?
Contraindicated in patients with history of arterial bleeding, immediately after childbirth and labor.

Dosage and when it is to be taken?
Adult: PO- Peripheral vascular disease: The recommended dose is 10-20 mg 3-4 times/day.
IV/IM- To arrest premature labour- The recommended dose is 200-500 mcg/min via IV infusion until control is achieved, then 10 mg 3-8 hourly via IM inj for several days.
 
How it should be taken?
It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein and large muscle.

Warning and Precautions:
Caution should be exercised in patients with history of bleeding problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Side Effects:
  • Central Nervous System: Dizziness
  • Heart: Low blood pressure, palpitations, flushing, fast heart rate, lung swelling.
  • Gastrointestinal: Nausea, vomitting and abdominal distress.
  • Miscellaneous: Rash and allergic reactions such as hives, difficulty breathing, tightness in the chest. 
Precautions:
Adverse Reactions:
On rare occasion oral administration of the drug has been associated in time with the occurrence of hypotension, tachycardia, chest pain, nausea, vomiting, dizziness, abdominal distress, and severe rash. If rash appears, the drug should be discontinued.
Although available evidence suggests a temporal association of these reactions with Isoxsuprine Hydrochloride, a causal relationship can be neither confirmed nor refuted.
Beta Adrenergic receptor stimulants such as Isoxsuprine Hydrocholoride have been used to inhibit pre-term labor.
Maternal and fetal tachycardia may occur under such use. Hypocalcemia, hypoglycemia, hypotension and ileus have been reported to occur in infants whose mothers received Isoxsuprine Hydrochloride. Pulmonary edema has been reported in mothers treated with beta stimulants. Isoxsuprine Hydrochloride is neither approved nor recommended for use in the treatment of premature labor.



Actoforan, Actofotan, Anti cancer, Mesothioloma, Phrma Brands, Taj Pharma Brands, Pharma brands, Pharma India brands

ACTOFORAN ® (PEMETREXED FOR INJECTION) A resource for patients with advanced nonsquamous non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM) to learn about ACTOFORAN ® therapy. ACTOFORAN ® is approved by the FDA in combination with cisplatin (another chemotherapy drug) for the initial treatment of advanced nonsquamous non-small cell lung cancer (NSCLC), a specific type of NSCLC. ACTOFORAN ® is not indicated for patients who have a different type of NSCLC called squamous cell. A product from TAJ PHARMA INDIA, As a wholly owned subsidiary of TAJ PHARMACEUTICALS GROUP - INDIA. 

 





Actoforan (Premetrexed for Injection) is used with another chemotherapy (anti-cancer) medication to treat malignant pleural mesothelioma (a type of cancer that affect the inside lining of the chest cavity). Premetrexed is also used to treat non-small cell lung cancer. 

Actoforan (Premetrexed for Injection) is a class of medications called antifolate antineoplastic agents. It works by blocking the action of a certain susbstance in the body that may help cancer cells multiply.

How should this medicine be used?
Actoforan (Premetrexed for Injection) comes as a solution (liquid) to be injected into a vein. Premetrexed is administered by a doctor or nurse in a medical office or infusion centre. It is usually given once every 21 days.

Your doctor will probably tell you to take other medications, such as folic acid (a vitamin), vitamin B12, and a corticosteroid such as dexamethasone (Tecadron) to decrease some of the side effects of this medication. Your doctor will give you directions for taking these medications. Follow your doctor'd directions carefully. Ask your doctor or pharmacist to explain any part you do not understand. If you miss a dose of one of these medications, call your doctor.

Your doctor will ask you to have regular blood tests before and during treatment with Actoforan (Premetrexed for Injection). Your doctor may change your dose of premetrexed or delay treatment based on the results of the blood tests.


Activital Fort, Cyanocobalamin, Brand India Pharma, Pharma India brands, Pharma Companies in India, Top 10 Pharma company, Taj PHarmaceuticals, Taj Pharma


Cyanocobalamin is also called vitamin B12. It is the most recently discovered of the viatmin B series, was isolated from the liver fraction in 1948. Cyanocobalamin is a complex water soluble compound. It is made up of a porphyrin like ring with a central cobalt atom attached to a nucleotide. It is required in body for growth, cell production and for blood and nerve function. The source of vitamin B12 is microbial synthesis, it is not present in plants or cereal grains to a measurable extent. The chief dietary source is microbially derived vitamin B12 in meat, eggs and dairy products. Humans must obtain the vitamin from the dietary intake of animal products.

It is the most famous vitamin of the family, because it is chemically the most air- stable, and it is the easiest to crystallize and therefore easiest to purify after it is produced by bacterial fermentation. A form of B12 called hydroxocobalamin is produced by bacteria, and then changed to cycobalamin in the process of being purified in activated charcoal columns after being separated from the bacterial cultures. Cyanide is naturally present in activated charcoal, and hydroxycobalamin, which has great affinity for cyanide, picks it up and is changed to cyanocobalamin. Thus, the cyanocobalamin form B12 is the most widespread in the food industry.

Indications
Cyanocobalamin is primarily indicated in conditions like Addisonian pernicious anaemia,Congenital cobalamine malabsorption,Congenital intrinsic factor deficiency,Homocystenemia,Ileal resection,Methylmalonylacidurias,Nutrition deficiency,Post gastrectomy vit B-12 deficiency,Transcobalamin II deficiency, and can also be given in adjunctive therapy as an alternative drug of choice in Vitamin-B12 defeciency of dietary origin.

Activital Fort- Presentation and Composition:
Strip of 10 Capsules
Each soft gelatin capsule contains:
Eicosapantaenoic acid- 90 mg
Docosahexanoic acid- 60 mg
Alpha- Lipoic Acid USP- 100 mg
Lycopene (10%)- 5 mg
Folic Acid- USP- 15 mg
Cyanocobalamin USP- 15 mg
Vitamin B6 (Pyridoxine hydrochloride) USP- 3 mg
Chromium Picolinate USP- 250 mcg
Selenious Acid USP equivalent to elemental selenium- 55 mcg
Zinc Sulphate monohydrate USP equivalent to elemental zonc- 15 mg
Manganese Sulphate USP equivalent to elemental Manganese- 2 mg
Light magnesium oxide USP equivalent to elemental magnesium- 40 mg
Excipients q.s

CONTRAINDICATIONS
Cyanocobalamin is contraindicated in conditions like Anaphylactic reactions, Tobacco amblyopia.

Friday 4 July 2014

Aciezyme-D, Pharma brand, Taj Brand, Taj Pharma, Taj Pharmaceuticals, Taj Drug


ACIEZYME-D SR Rabeprazole is a PPI that suppresses gastric acid secretion by inhibiting the gastric H+/K+ ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, rabeprazole has been characterized as a gastric proton pump inhibitor. Rabeprazole blocks the final step of gastric acid secretion. Onset of action is 1 hour. Duration 24 hours. Absorption Oral bioavailability is about 52% and peak plasma concentrations are reached about 3.5 hr after oral admin. The median inhibitory effect of rabeprazole on 24 hour gastric acidity is 88% of maximal after the first dose.

ACIEZYME-D SR Domperidone is a dopamine antagonist with anti-emetic properties domperidone does not readily cross the blood-brain barrier. Its anti-emetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone, which lies outside the blood-brain barrier in the area postrema. Studies in man have shown oral domperidone to increase lower esophaegeal pressure, improve antroduodenal motility and accelerate gastric emptying. There is no effect on gastric secretion.
In fasting subjects, domperidone is rapidly absorbed after oral administration, with peakplasma concentrations at 30 to 60 minutes. The low absolute bioavailability of oral domperidone (approximately 15%) is due to an extensive first-pass metabolism in the gut wall and liver. Although domperidone`s bioavailability is enhanced in normal subjects when taken after a meal, patients with gastro-intestinal complaints should take domperidone 15-30 minutes before a meal. Reduced gastric acidity impairs the absorption of domperidone.

FORMULATIONS AVAILABLE: CAPSULE ACIEZYME-D SR
Each Hard Gelatin Capsule contains:
Rabeprazole Sodium USP (as enteric coated) 20 mg
Domperidone Maleate USP (= to Domperidone) (10 mg as IR, 20 mg as SR) 30 mg

DOSAGE AND ADMINISTRATION: One capsule once daily.

INDICATIONS:
Aciezyme-D is indicated for the relief of symptoms of
  1. Dyspepsia
  2. GERD
  3. Nausea associated with acid peptic disorders
  4. Post-operative nausea and vomiting
  5. Chronic gastritis

Pharma India Brands Taj Products :: Taj Pharmaceuticals Pharma Brand Brand India Pharma Pharma Companies in India 'Brand India Pharma' promotion Top 10 Pharma Companies,

Taj Pharmaceuticals is one of the India’s leading innovation-driven healthcare groups. Its core businesses are pharmaceuticals and diagnostics. Taj Pharmaceuticals is number one in the global diagnostics market and is the leading supplier of pharmaceuticals for cancer and a leader in virology and transplantation. As a supplier of products and services for the prevention, diagnosis and treatment of disease, the Group contributes on a broad range of fronts to improving people’s health and quality of life. Taj Pharmaceuticals employs roughly 2,000+ people in 24 countries.

Taj Pharmaceutical's pioneering approach to healthcare innovation enables us to deliver significant benefits to patients as well as to healthcare providers and systems. In our vision of the future, therapies will be available for many of today's untreatable diseases, it will be possible to optimize drug efficacy and safety, and effective strategies will be in place for preventing disease. Early diagnosis and improved new treatments will significantly reduce the need for expensive surgical operations and long hospital stays.

With medicines across 31 therapeutic areas, we help to treat and prevent many of the most common, and most challenging, conditions of our time. We also build partnerships to help ensure access to our medicines and educate and empower consumers. And, with a broad range of animal vaccines and medicines, we help to protect the health of both pets and farm animals.

While this vision is an aspiration for the future, Taj Pharmaceuticals has begun pioneering the path, with a wide range of products and services available to:
















































































































Taj Pharma is one of the largest generic pharmaceutical company in India. We hold top positions in different established markets worldwide and are building a strong presence in many emerging generics markets.

Today, we market more than 500 branded and 4600 generics compositions to consumers in more than 40 countries and territories across the globe. Our products cover a vast array of therapeutic categories, and we offer an extensive range of dosage forms and delivery systems including oral solids, controlled-release, steriles, injectables, topicals, liquids, transdermals, semi-solids and high-potency products.

capsules
At Taj Pharma, we are always ready to meet the challenges of the dynamic global pharmaceutical industry with its numerous and wide-ranging issues – from complex research, development and regulatory conditions to rapidly changing consumer demands.

Our Generics portfolio offers over 1500 products in the major therapeutic areas of gastro-intestinal, cardiovascular, pain management, oncology, anti-infectives, paediatrics and dermatology. Brands like Alzocum®,
Benacof, Wallbrurate®, Coversec, Cadrol, Humogen and Merokem enjoy leadership positions in several key markets, including India, Russia & other countries.

Our deep customer relationships, quality medicines and consistently delivered promise make us a trusted brand across the world.

We have capitalized on every opportunity to bring our high-quality products to more people around the world. A synchronized supply chain that leverages our strong product development capabilities, state-of-the-art manufacturing and vertical integration with our own APIs has created a creditable track record of successful launches.
generic medicines
Our generics offerings deliver quality at cost-effective prices in the highly regulated markets of the United States, UK and other Asian countries.

  

 Note : This product information is intended only for residents of the India. Taj Pharmaceuticals Limited,  medicines help to treat and prevent a range of conditions—from the most common to the most challenging—for people around the world.


Information for Health Care Professionals

*** Please consult local Prescribing Information for any product before use. This website is an international information resource for healthcare professionals with an interest in disease management. This website is not intended to replace the advice of a qualified healthcare professional. Above brand is a trademark of the Taj group of companies (Taj Pharmaceuticals Limited).