Adrenilan, Taj Pharmaceuticals, Taj Pharma, Pharma India Brands, Pharma Brands, Taj Drugs, Taj brands, Vasodilator

ISOXSUPRINE (eye SOX syoo preen) is a type of vasodilator. This medicine is used to treat problems that result from poor blood circulation. It is also used to treat the symptoms of certain types of dementia. This medication is prescribed for peripheral vascular disease, relief of symptoms associated with cerebrovascular insufficiency, and premature labor.  It relaxes blood vessels, which makes them wider and allows blood to pass through them more easily.
 
When it is not to be taken?
Contraindicated in patients with history of arterial bleeding, immediately after childbirth and labor.

Dosage and when it is to be taken?
Adult: PO- Peripheral vascular disease: The recommended dose is 10-20 mg 3-4 times/day.
IV/IM- To arrest premature labour- The recommended dose is 200-500 mcg/min via IV infusion until control is achieved, then 10 mg 3-8 hourly via IM inj for several days.

 

How it should be taken?

It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein and large muscle.

Warning and Precautions:

Caution should be exercised in patients with history of bleeding problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Side Effects:

• Central Nervous System: Dizziness
• Heart: Low blood pressure, palpitations, flushing, fast heart rate, lung swelling.
• Gastrointestinal: Nausea, vomitting and abdominal distress.
• Miscellaneous: Rash and allergic reactions such as hives, difficulty breathing, tightness in the chest. 

Precautions:

Adverse Reactions:

On rare occasion oral administration of the drug has been associated in time with the occurrence of hypotension, tachycardia, chest pain, nausea, vomiting, dizziness, abdominal distress, and severe rash. If rash appears, the drug should be discontinued.

Although available evidence suggests a temporal association of these reactions with Isoxsuprine Hydrochloride, a causal relationship can be neither confirmed nor refuted.
Beta Adrenergic receptor stimulants such as Isoxsuprine Hydrocholoride have been used to inhibit pre-term labor.
Maternal and fetal tachycardia may occur under such use. Hypocalcemia, hypoglycemia, hypotension and ileus have been reported to occur in infants whose mothers received Isoxsuprine Hydrochloride. Pulmonary edema has been reported in mothers treated with beta stimulants. Isoxsuprine Hydrochloride is neither approved nor recommended for use in the treatment of premature labor.